N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate

CAS: 1026256-93-8

Ref. TR-B206670

Produktinformation

• Name: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate
• Synonyme: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyO-phenylCarbamate

Beschreibung

Applications N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic.
References Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991); Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1992); McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 313.37
• Formel: C₁₇H₁₅NO₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C17H15NO3S/c1-12(16-11-13-7-5-6-10-15(13)22-16)18(20)17(19)21-14-8-3-2-4-9-14/h2-12,20H,1H3
• InChI Key: InChIKey=JTKHUJNVHQWSAY-UHFFFAOYSA-N
• SMILES: CC(C)CCCCCCCCO