(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester

CAS: 32981-85-4

Ref. TR-B208560

Produktinformation

• Name: (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
• Synonyme: (2R,3S)-Methyl 3-benzoylamino-2-hydroxy-3-phenylpropanoate, (2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester, LKT-T 0104, Methyl (-)-(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate, Methyl (2R,3S)-N-benzoylphenylisoserinate,Isoserine, N-benzoyl-3-phenyl-, methyl ester, (2R,3S)- (8CI), Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, methyl ester, (alphaR,betaS)-, Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, methyl ester, [R-(R*,S*)]-, (2R,3S)-1-benzoyl-2-hydroxy-3-aminophenylpionic acid ester, Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-, Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, [R-(R*,S*)]-, Isoserine, N-benzoyl-3-phenyl-, methyl ester, (2R,3S)-, Lkt-T 0104, Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoale, Methyl(2R,3S)-N-benzoylphenylisoserinate, Methyl-(2R,3S)-N-Benzoyl-3-Phenylisos, N-Benzoyl-3-Phenyl isoserine methyl ester, Paclitaxel Side Chain No.4, methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate, methyl (2R,3S)-3-benzamido-2-hydro-3-phenylpropionate, methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropionate

Beschreibung

Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.
References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 299.32
• Formel: C₁₇H₁₇NO₄
• Farbe/Form: Off White Powder
• InChl: InChI=1S/C17H17NO4/c1-22-17(21)15(19)14(12-8-4-2-5-9-12)18-16(20)13-10-6-3-7-11-13/h2-11,14-15,19H,1H3,(H,18,20)/t14-,15+/m0/s1
• InChI Key: InChIKey=WKRLQDKEXYKHJB-LESCRADOSA-N
• SMILES: C[C@]12CC[C@@H]3C(=CCc4cc(O)ccc43)[C@H]1CCC2=O