5-(Benzyloxy)-2-((benzyloxy)carbonyl)-3-hydroxy-5-oxopentanoic Acid

Ref. TR-B224985

Produktinformation

• Name: 5-(Benzyloxy)-2-((benzyloxy)carbonyl)-3-hydroxy-5-oxopentanoic Acid
• Synonyme: 3-hydroxy-5-oxo-5-phenylmethoxy-2-phenylmethoxycarbonylpentanoic acid

Beschreibung

Applications 5-(Benzyloxy)-2-((benzyloxy)carbonyl)-3-hydroxy-5-oxopentanoic Acid is an intermediate used in the synthesis of 2-[2-[(5-carboxypentyl)amino]-2-oxoethyl]-2-hydroxybutanedioic Acid (C181175), which is derived from Methyl 6-Aminohexanoate Hydrochloride (M287100), which is used as a reagent to synthesize straight chain hydroxamates, compounds that act as inhibitors of Human Histone Deacetylase (HDAC) that have the potential to treat cancer. Methyl 6-aminohexanoate is also sometimes used as a spacer unit for peptide synthesis.
References Matthews, S., et al.: J. Chem. Soc. Chem. Commun., 17, 1809 (1995); Remiszewski, S., et al.: J. Med. Chem., 45, 753 (2002)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 372.369
• Formel: C₂₀H₂₀O₇
• Farbe/Form: Neat
• InChl: InChI=1S/C20H20O7/c21-16(11-17(22)26-12-14-7-3-1-4-8-14)18(19(23)24)20(25)27-13-15-9-5-2-6-10-15/h1-10,16,18,21H,11-13H2,(H,23,24)
• InChI Key: InChIKey=KCPWVFMFMZNCJR-UHFFFAOYSA-N
• SMILES: O=C(CC(O)C(C(=O)O)C(=O)OCc1ccccc1)OCc1ccccc1