9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol Maleate

CAS: 113108-86-4

Ref. TR-B230000

Produktinformation

• Name: 9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol Maleate
• Synonyme: 9-(benzylamino)-1,2,3,4-tetrahydroacridin-1-ol;(Z)-but-2-enedioic acid
• Marke: TRC

Beschreibung

Stability Store in freezer at -20°C
Applications A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans. Also showed potent in vitro inhibition of the uptake of radiolabeled noradrenaline and dopamine.
References Shutske, G.M., et al.: J. Med. Chem., 32, 1805 (1989)

Chemische Eigenschaften

• Molekulargewicht: 420.46
• Formel: C₂₀H₂₀N₂O·C₄H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C20H20N2O.C4H4O4/c23-18-12-6-11-17-19(18)20(15-9-4-5-10-16(15)22-17)21-13-14-7-2-1-3-8-14;5-3(6)1-2-4(7)8/h1-5,7-10,18,23H,6,11-13H2,(H,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI Key: InChIKey=JRQSVNSUJOFXHC-BTJKTKAUSA-N
• SMILES: O=C(O)/C=C\C(=O)O.OC1CCCc2nc3ccccc3c(NCc3ccccc3)c21