O6-Benzylguanine

CAS: 19916-73-5

Ref. TR-B278500

Produktinformation

• Name: O6-Benzylguanine
• Synonyme: 6-(Phenylmethoxy)-9H-purin-2-amine, 1H-Purin-2-amine, 6-(phenylmethoxy)- (9CI), Purine, 2-amino-6-(benzyloxy)- (7CI,8CI), 2-Amino-6-(benzyloxy)purine, 2-Amino-6-(phenylmethoxy)-9H-purine, 6-(Benzyloxy)guanine, 6-O-Benzylguanine, NSC 637037, 1H-Purin-2-amine, 6-(phenylmethoxy)-, 2-Amino-6-Benzyloxypurine, 6-(benzyloxy)-7H-purin-2-amine, 6-Benzyloxy Guanine, 9H-Purin-2-amine, 6-(phenylmethoxy)-, Benzylguanine, O⁶-Benzylguanine, Purine, 2-amino-6-(benzyloxy)-
• CAS: 19916-73-5

Beschreibung

Applications An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.
References Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 241.25
• Formel: C₁₂H₁₁N₅O
• Farbe/Form: Off-White to Yellow Solid
• InChl: InChI=1S/C12H11N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H3,13,14,15,16,17)
• InChI Key: InChIKey=KRWMERLEINMZFT-UHFFFAOYSA-N
• SMILES: Nc1nc(OCc2ccccc2)c2nc[nH]c2n1