1-Benzylindole-5-boronic Acid Pinacol Ester

CAS: 1206163-56-5

Ref. TR-B279973

Produktinformation

• Name: 1-Benzylindole-5-boronic Acid Pinacol Ester
• Synonyme: 1-(Phenylmethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Beschreibung

Applications 1-Benzylindole-5-boronic Acid Pinacol Ester acts as a reagent in the synthesis of 3,3-difluoro-2-oxindoles via electrophilic fluorination of indoles using N-fluorobenzenesulfonimide. Preparation of triazolopyridine compounds as JAK kinase inhibitors useful in the treatment of neurodegenerative and inflammatory diseases.
References : Lim, Y., et al.: Org. Lett., 14, 5676; Menet, C., et al.: PCT Int. Appl. (2010), WO 2010010190 A1 20100128.

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 333.23
• Formel: C₂₁H₂₄BNO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C21H24BNO2/c1-20(2)21(3,4)25-22(24-20)18-10-11-19-17(14-18)12-13-23(19)15-16-8-6-5-7-9-16/h5-14H,15H2,1-4H3
• InChI Key: InChIKey=ZJVGZQOSLAZPOI-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2ccc3c(ccn3Cc3ccccc3)c2)OC1(C)C