rac-6-Benzyloxy-8-(oxiran-2-yl)-4H-benzo[1,4]oxazin-3-one

CAS: 869478-12-6

Ref. TR-B287540

Produktinformation

• Name: rac-6-Benzyloxy-8-(oxiran-2-yl)-4H-benzo[1,4]oxazin-3-one
• Synonyme: 8--Oxiranyl-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one
• Marke: TRC

Beschreibung

Applications rac-6-Benzyloxy-8-(oxiran-2-yl)-4H-benzo[1,4]oxazin-3-one is an racemic intermediate in the synthesis of Olodaterol (O262000), a novel inhaled β2-adrenoceptor agonist with a 24h bronchodilatory efficacy.
References Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);

Chemische Eigenschaften

• Molekulargewicht: 297.31
• Formel: C₁₇H₁₅NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C17H15NO4/c19-16-10-22-17-13(15-9-21-15)6-12(7-14(17)18-16)20-8-11-4-2-1-3-5-11/h1-7,15H,8-10H2,(H,18,19)
• InChI Key: InChIKey=QKZJSZZMIRDNNQ-UHFFFAOYSA-N
• SMILES: O=C1COc2c(cc(OCc3ccccc3)cc2C2CO2)N1