(S)-Bepotastine Besylate

CAS: 190786-44-8

Ref. TR-B317000

Produktinformation

• Name: (S)-Bepotastine Besylate
• Synonyme: 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, benzenesulfonate (1:1), 1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, (S)-, monobenzenesulfonate, 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, monobenzenesulfonate (9CI), (S)-4-[4-(4-chlorophenyl-2-pyridylmethoxy)piperidinyl]butyric acid benzenesulfonate, BB, Bepotastine benzenesulfonate, Bepotastine benzenesulfonate salt, Bepotastine besilate, Bepotastine besylate, Bepreve, Betatastine, TAU 284, Talion, Tarion, 1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, (S)-, monobenzenesulfonate, 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, benzenesulfonate (1:1), 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, monobenzenesulfonate

Beschreibung

Stability Hygroscopic
Applications Bepotastine is a histamine H1 receptor antagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).
References Kaminuma, O. et al.: Biol. Pharm. Bull., 21, 411 (1998); Kitaba, S. et al.: J. Allergy, No pp. given (2008); Lyseng-Williamson, K.A., Drugs, 70, 1579 (2010);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 547.06
• Formel: C₂₁H₂₅ClN₂O₃·C₆H₆O₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C21H25ClN2O3.C6H6O3S/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26;7-10(8,9)6-4-2-1-3-5-6/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26);1-5H,(H,7,8,9)/t21-;/m0./s1
• InChI Key: InChIKey=UDGHXQPQKQPSBB-BOXHHOBZSA-N
• SMILES: O=C(O)CCCN1CCC(O[C@@H](c2ccc(Cl)cc2)c2ccccn2)CC1.O=S(=O)(O)c1ccccc1