Betamethasone 21-Phosphate Disodium Salt

CAS: 151-73-5

Ref. TR-B327030

Produktinformation

• Name: Betamethasone 21-Phosphate Disodium Salt
• Synonyme: Dexamethasone Sodium Phosphate Imp. B (EP), Betamethasone Sodium Phosphate, (11beta,16beta)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione sodium salt (1:2), (11beta,16beta)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium salt, 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) disodium salt, Bentelan, Betamethasone 21-disodium phosphate, Betamethasone disodium phosphate, Betamethasone sodium phosphate, Betnesol, Celestan solubile, Disodium betamethasone 21-phosphate, Durabetason, NSC 90616, Steronema, Vista-Methasone, CCI 1517, Dexamethasone Sodium Phosphate Impurity B as Disodium Salt, Dexamethasone Phosphate Impurity B as Disodium Salt, 1,4-Pregnadien-9-Alpha-Fluoro-16-Beta-Methyl-11-Beta, 17,21-Triol-3,20-Dione 21-Phosphate, Disodium Salt, 20-Dione,9-Fluoro-11-Beta,17,21-Trihydroxy-16-Beta-Methyl-Pregna-4-Diene-3, 21-(Dihydrogenphosphate),Disodiumsalt, 9A-Fluoro-16B-Methylprednisolone-21-(Disodium Phosphate), Beta Methasone Sodium Phosphate, Betamethasone 21-(Disodium Phosphate), Betamethasone 21-Phosphate Disodium, Betamethasone 21-Phosphate Sodium Salt, Betamethasonedisodiumphosphate, Betmethasone Disodium Phosphate, Celestan, Disodium (11Beta,16Beta)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Phosphate, Nsc 90616, Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11,17-Dihydroxy-16-Methyl-21-(Phosphonooxy)-,DisodiumSalt,(11Beta,16Beta)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11beta,16beta)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, sodium salt (1:2), (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate), disodium salt, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate), disodium salt (7CI, 8CI)

Beschreibung

Impurity Dexamethasone Sodium Phosphate EP Impurity B
Stability Hygroscopic
Applications Betamethasone 21-Phosphate Disodium Salt (Dexamethasone Sodium Phosphate EP Impurity B) is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.
References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 516.40
• Formel: C₂₂H₂₈FO₈PNa
• Farbe/Form: Neat
• InChl: , /h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30), /q, 2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-, /m0../s1, InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30, ,
• SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-].[Na+].[Na+]