Betulin-d3

CAS: 473-98-3

Ref. TR-B330242

Produktinformation

• Name: Betulin-d3
• Synonyme: Lup-20(29)-ene-3β,28-diol-d3, Lup-20(30)-ene-3β,28-diol-d3, 3,28-Dihydroxy-lupeol-d3, 3β,28-Dihydroxylup-20(29)-ene-d3, Betuline-d3, Betulinic Alcohol-d3, Betulinol-d3, Betulol-d3, NSC 4644-d3, Trochol-d3
• Marke: TRC

Beschreibung

Applications Betulin-d3 is the isotope labelled analog of Betulin (B330240); a derivative of Betulinic Acid (B330250) which is a compound used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
References Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010)

Chemische Eigenschaften

• Molekulargewicht: 445.74
• Formel: C₃₀H₄₇D₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22?,23+,24-,25+,27?,28?,29?,30+/m0/s1/i12D2,24D
• InChI Key: InChIKey=BLQSPZHGZHJLGB-CLFAGFIQSA-N
• SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CCl)OC(=O)CCCCCCC/C=C\CCCCCCCC