Bexarotene

CAS: 153559-49-0

Ref. TR-B336750

Produktinformation

• Name: Bexarotene
• Synonyme: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic Acid, LG 100069, LG 1069, LG 69, LGD 1069, RO 26-4455, SR 11247, Targret, Targretin, Targretyn, Targrexin, 1-Bexarotene, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic Acid, SR-11247, LGD-1069, Targretin, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid, Benzoic acid, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-, LG 69 (retinoid), Lg 100069, Lg 1069, Lg 69, Lgd 1069, Lgd1069, Ro 26-4455, Sr 11247
• CAS: 153559-49-0

Beschreibung

Applications Bexarotene is a selective retinoid X receptor (RXR) agonist and an antineoplastic agent (1,2,3).
References (1) Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994) (2) Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996) (3) Mukherjee, R., et al.: Nature, 386, 407 (1997)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 348.48
• Formel: C₂₄H₂₈O₂
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
• InChI Key: InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N
• SMILES: C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C