O-Benzyl Ganciclovir N-Formamide Diacetate

Ref. TR-B412345

Produktinformation

• Name: O-Benzyl Ganciclovir N-Formamide Diacetate
• Synonyme: [3-acetyloxy-2-[(2-formamido-6-phenylmethoxypurin-9-yl)methoxy]propyl] acetate
• Marke: TRC
• Beschreibung: Applications O-Benzyl Ganciclovir N-Formamide is an intermediate used in the synthesis of Valganciclovir N3,N3'-Methylene Dimer (>90%) (V092015), which is an impurity of Valganciclovir (V092000), a pro-drug of Ganciclovir (G235000) . Used in treatment of retro-virus.References Acosta, E., et al.: Clin. Pharmacol. Ther., 81, 867 (2007), Nassetta, L., et al.: J. Antimicrob. Chemother., 63, 862 (2009),

Chemische Eigenschaften

• Molekulargewicht: 457.437
• Formel: C₂₁H₂₃N₅O₇
• Farbe/Form: Neat
• InChl: InChI=1S/C21H23N5O7/c1-14(28)30-9-17(10-31-15(2)29)33-13-26-11-22-18-19(26)24-21(23-12-27)25-20(18)32-8-16-6-4-3-5-7-16/h3-7,11-12,17H,8-10,13H2,1-2H3,(H,23,24,25,27)
• InChI Key: InChIKey=GCSWAQHZQFTPHY-UHFFFAOYSA-N
• SMILES: CC(=O)OCC(COC(C)=O)OCn1cnc2c(OCc3ccccc3)nc(NC=O)nc21