Bleomycin A5 Hydrochloride Salt

CAS: 55658-47-4

Ref. TR-B595750

Produktinformation

• Name: Bleomycin A5 Hydrochloride Salt
• Synonyme: [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4R)-5-[[(2S,3R)-1-[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-4-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate;hydrochloride, Bleomycin A₅ hydrochloride, Bleomycinamide, N¹-[3-[(4-aminobutyl)amino]propyl]-, hydrochloride, Bleomycinamide, N¹-[3-[(4-aminobutyl)amino]propyl]-, hydrochloride (1:?), N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide hydrochloride

Beschreibung

Stability Hygroscopic
Applications Bleomycin A5 Hydrochloride Salt is used as an anti-cancer drug used to combat various forms of carcinoma via activated-apoptosis of cancer cells.
References Zochowska, M. et al.: PLoS One, 4 (2009); Zhao, J. et al.: Med. Onc., 28, 354 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 1477.02
• Formel: C₅₇H₈₉N₁₉O₂₁S₂·ClH
• Farbe/Form: White To Light Yellow
• InChl: InChI=1S/C57H89N19O21S2.ClH/c1-22-35(73-48(76-46(22)61)27(14-33(60)80)68-15-26(59)47(62)86)52(90)75-37(43(28-16-65-21-69-28)95-56-45(41(84)39(82)31(17-77)94-56)96-55-42(85)44(97-57(63)92)40(83)32(18-78)93-55)53(91)70-24(3)38(81)23(2)49(87)74-36(25(4)79)51(89)67-13-8-34-71-30(20-98-34)54-72-29(19-99-54)50(88)66-12-7-11-64-10-6-5-9-58;/h16,19-21,23-27,31-32,36-45,55-56,64,68,77-79,81-85H,5-15,17-18,58-59H2,1-4H3,(H2,60,80)(H2,62,86)(H2,63,92)(H,65,69)(H,66,88)(H,67,89)(H,70,91)(H,74,87)(H,75,90)(H2,61,73,76);1H/t23-,24-,25-,26+,27+,31+,32-,36+,37+,38+,39-,40-,41+,42+,43+,44+,45+,55-,56+;/m1./s1