(S)-1-Boc-3-hydroxypiperidine-d4

CAS: 143900-44-1

Ref. TR-B656652

Produktinformation

• Name: (S)-1-Boc-3-hydroxypiperidine-d4
• Synonyme: tert-butyl (3S)-2,2,6,6-tetradeuterio-3-hydroxypiperidine-1-carboxylate, (S)-1-N-Boc-3-Hydroxy-Piperidine, (S)-3-Hydroxy-Piperidine-1-Carboxylic Acid Tert-Butyl Ester, (S)-3-Hydroxy-1-(Tert-Butoxycarbonyl)Piperidine, (S)-1-Boc-3-Piperidinol, (S)-N-(Tert-Butoxycarbonyl)-3-Hydroxypiperidine Hydrochloride, (S)-N-Boc-3-Hydroxy Piperidine, (S)-Tert Butyl-3-Hydroxypiperidine-1-Carboxylate, tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate, (S)-N-BOC-3-piperidinol, (S)-N-Boc-3-piperidine

Beschreibung

Applications (S)-1-Boc-3-hydroxypiperidine-d4 is an intermediate in synthesizing Ibrutinib-d4 (I124971), a labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 205.287
• Formel: C₁₀D₄H₁₅NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h8,12H,4-7H2,1-3H3/t8-/m0/s1/i6D2,7D2
• InChI Key: InChIKey=UIJXHKXIOCDSEB-ODROFLNISA-N
• SMILES: [2H]C1([2H])CC[C@H](O)C([2H])([2H])N1C(=O)OC(C)(C)C