(1S,2S)-Bortezomib

CAS: 1132709-14-8

Ref. TR-B675715

Produktinformation

• Name: (1S,2S)-Bortezomib
• Synonyme: B-[(1S)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic Acid, bortezomib diastereomer (S,S) (USP)
• CAS: 1132709-14-8

Beschreibung

Impurity Bortezomib USP Impurity G
Stability Hygroscopic
Applications (1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hardy, J. et al.: Science, 297, 353 (2002); Paris, D. et al.: Mol. Med. 17, 149 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 384.24
• Formel: C₁₉H₂₅BN₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17+/m0/s1