(-)-cis-anti-N2-BPDE-dG

CAS: 66113-73-3

Ref. TR-B676635

Produktinformation

• Name: (-)-cis-anti-N2-BPDE-dG
• Synonyme: [7S-(7α,8β,9β,10β)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine, Benzo[a]pyrene Guanosine deriv., (-)-cis-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene
• Marke: TRC
• Beschreibung: Applications (-)-cis-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair.References Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000)

Chemische Eigenschaften

• Molekulargewicht: 569.57
• Formel: C₃₀H₂₇N₅O₇
• Farbe/Form: Neat
• InChl: InChI=1S/C30H27N5O7/c36-10-18-17(37)9-19(42-18)35-11-31-24-28(35)33-30(34-29(24)41)32-23-22-15-7-6-13-3-1-2-12-4-5-14(21(15)20(12)13)8-16(22)25(38)27(40)26(23)39/h1-8,11,17-19,23,25-27,36-40H,9-10H2,(H2,32,33,34,41)/t17-,18+,19+,23-,25-,26-,27+/m0/s1
• InChI Key: InChIKey=AWARIMYXKAIIGO-FIIMHDCBSA-N
• SMILES: C[C@]12CC[C@@H]3c4ccc(O)cc4/C(=N/OCC(=O)O)C[C@H]3[C@@H]1CC[C@@H]2O