Brevianamide F

CAS: 38136-70-8

Ref. TR-B677395

Produktinformation

• Name: Brevianamide F
• Synonyme: (3S,8aS)-Hexahydro-3-(1H-indol-3-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione, Cyclo(L-Pro-L-Trp), Cyclo-L-tryptophyl-L-proline, L-Prolyl-L-tryptophan Anhydride Prolyltryptophanyldiketopiperazine, Cyclo-L-Prolyl-L-tryptophanyl, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)-, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S-trans)-

Beschreibung

Applications Brevianamide F is used in the preparation, reactions, medicinal and cheical propreties of diketopiperazines as bioactive natural products. Acts as a reagent in the total synthesis and antitumor activity in vitro of glioperazine C and its derivatives, synthesis and biological evaluation of a post-synthetically trp-based diketopiperazine and it’s antitumor structure-activity relationship.
References Wang, P., et al.: J. Chem. Pharma. Res., 7, 85 (2015); Preciado, S., et al.: MedChemComm, 4, 1171 (2013); Borthwick, A. D., et al.: Chem. Rev., 112, 3641 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 283.33
• Formel: C₁₆H₁₇N₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C16H17N3O2/c20-15-14-6-3-7-19(14)16(21)13(18-15)8-10-9-17-12-5-2-1-4-11(10)12/h1-2,4-5,9,13-14,17H,3,6-8H2,(H,18,20)/t13-,14-/m0/s1
• InChI Key: InChIKey=RYFZBPVMVYTEKZ-KBPBESRZSA-N
• SMILES: O=C1N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N2CCC[C@@H]12