O-Desmethyl Brinzolamide-(Ethyl-D5)

CAS: 186377-56-0

Ref. TR-B677612

Produktinformation

• Name: O-Desmethyl Brinzolamide-(Ethyl-D5)
• Synonyme: (4R)-2-(3-hydroxypropyl)-1,1-dioxo-4-(1,1,2,2,2-pentadeuterioethylamino)-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide

Beschreibung

Applications O-Desmethyl Brinzolamide-D5 is a labelled analogue of O-Desmethyl Brinzolamide (B677610). O-Desmethyl Brinzolamide is a derivative of Brinzolamide (B677601), a carbonic anhydrase inhibitor that is used as an ocular topical treatment for patients experiencing intraocular pressure. Brinzolamide reduces pressure by reducing the rate of aqueous humour formation.
References Cvetkovic, R. & Perry, C.: Drugs & Aging, 20, 919 (2003); Ermis, S., et al.: Eye, 19, 303 (2005); Silver, L., et al.: Surv. Ophthalmol., 44, S147 (2000)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 374.512
• Formel: C₁₁D₅H₁₄N₃O₅S₃
• Farbe/Form: Neat
• InChl: InChI=1S/C11H19N3O5S3/c1-2-13-9-7-14(4-3-5-15)22(18,19)11-8(9)6-10(20-11)21(12,16)17/h6,9,13,15H,2-5,7H2,1H3,(H2,12,16,17)/t9-/m0/s1/i1D3,2D2
• InChI Key: InChIKey=WQSYAXSFXFVBTJ-MOVPIWGISA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])N[C@H]1CN(CCCO)S(=O)(=O)c2sc(S(N)(=O)=O)cc21