2-Bromobenzyl Alcohol

CAS: 18982-54-2

Ref. TR-B679995

Produktinformation

• Name: 2-Bromobenzyl Alcohol
• Synonyme: 2-Bromobenzenemethanol, 1-Bromo-2-(hydroxymethyl)benzene, 2-(Hydroxymethyl)phenyl Bromide, o-Bromo-benzyl Alcohol, 2-Bromophenylmethanol, 2-Hydroxymethyl-1-bromobenzene, o-Bromobenzyl Alcohol, (2-Bromophenyl)Methanol, 2-(Hydroxymethyl)phenyl bromide, Benzenemethanol, 2-bromo-, Benzyl alcohol, o-bromo-, O-Bromobenzyl Alcohol

Beschreibung

Applications 2-Bromobenzyl Alcohol acts as a reagent for the synthesis of alkoxy tetrasubstituted chiral amino acids via three-component reaction of (diazo)oxindoles, alcohols and benzhydrylimino ester involving enantioselective trapping of oxonium ylides by benzhydrylimino ester. Also acts as a reagent for the preparation of orally active and liver-targeted prodrug of 5-fluoro-2'-deoxyuridine for treatment of hepatocellular carcinoma.
References Jia, S., et al.: Chin. Chem. Lett., PagesAhead of Print (2016); Peng, Y., et al.: J. Med. Chem., 59, 3661 (2016)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 187.03
• Formel: C₇H₇BrO
• Farbe/Form: Neat
• InChl: InChI=1S/C7H7BrO/c8-7-4-2-1-3-6(7)5-9/h1-4,9H,5H2
• InChI Key: InChIKey=IOWGHQGLUMEZKG-UHFFFAOYSA-N
• SMILES: OCc1ccccc1Br