8-Bromoguanosine-13C2,15N

CAS: 4016-63-1

Ref. TR-B684366

Produktinformation

• Name: 8-Bromoguanosine-13C2,15N
• Synonyme: 2-Amino-8-bromo-6-hydroxypurine Riboside-13C2,15N, NSC 174257-13C2,15N, NSC 79211-13C2,15N, 2-Amino-8-bromo-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one, 2-Amino-8-bromo-9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one, 2-Amino-8-bromo-9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-6,9-dihydro-1H-purin-6-one, 2-amino-8-bromo-9-beta-D-glycero-pentofuranosyl-5,9-dihydro-6H-purin-6-one, 2-amino-8-bromo-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one, 8-Bromo-Guanosine, 8-Bromoguanosine hydrate, Chembridge 5141604, Guanosine, 8-bromo-, NSC 174257, NSC 79211, 8-Bromoguanosine

Beschreibung

Applications 8-Bromoguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 365.115
• Formel: C₂C₈H₁₂BrNN₄O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C10H12BrN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2-,4-,5-,8-/m1/s1/i3+1,6+1,13+1
• InChI Key: InChIKey=ASUCSHXLTWZYBA-XEEJASCLSA-N
• SMILES: Nc1n[13c]2[13c]([15n]c(Br)n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1