2-Bromo 17β-Estradiol

CAS: 15833-07-5

Ref. TR-B684970

Produktinformation

• Name: 2-Bromo 17β-Estradiol
• Synonyme: 2-Bromo-estradiol, 2-Bromo-1,3,5(10)-estratriene-3,17ß-diol, 2-Bromo-ß-estradiol, 2-Bromoestradiol, NSC 105460, Estra-1,3,5(10)-Triene-3,17-Diol, 2-Bromo-, 2-Bromoestra-1(10),2,4-Triene-3,17-Diol

Beschreibung

Stability Light Sensitive
Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.
References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 351.28
• Formel: C₁₈H₂₃BrO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C18H23BrO2/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-16(20)15(19)9-13(10)11/h8-9,11-12,14,17,20-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1
• InChI Key: InChIKey=SORISAYAZBCIQH-XSSYPUMDSA-N
• SMILES: C[C@]12CC[C@@H]3c4cc(Br)c(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O