4-Bromo 17β-Estradiol

CAS: 1630-83-7

Ref. TR-B684975

Produktinformation

• Name: 4-Bromo 17β-Estradiol
• Synonyme: 4-Bromo-estra-1,3,5(10)-triene-3,17ß-diol, 4-Bromo-1,3,5(10)-estratriene-3,17ß-diol, 4-Bromo-17ß-estradiol, 4-Bromo-ß-estradiol, 4-Bromoestradiol, NSC 104802

Beschreibung

Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.
References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 351.28
• Formel: C₁₈H₂₃BrO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C18H23BrO2/c1-18-9-8-11-10-4-6-15(20)17(19)13(10)3-2-12(11)14(18)5-7-16(18)21/h4,6,11-12,14,16,20-21H,2-3,5,7-9H2,1H3/t11-,12-,14+,16+,18+/m1/s1
• InChI Key: InChIKey=WSJCDIBESNMSPH-ZHIYBZGJSA-N
• SMILES: C[C@]12CC[C@@H]3c4ccc(O)c(Br)c4CC[C@H]3[C@@H]1CC[C@@H]2O