2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene

CAS: 1030825-20-7

Ref. TR-B685970

Produktinformation

• Name: 2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene
• Synonyme: 2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene, Thiophene, 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)-, 2-(5-Bromo-2-Methylbenzyl)-5-(4-fluorophenyl)thiophene, 2-[(5-Bromo-2-methyl phenyl)methyl]-5-(4-fluorophenyl)thiophene, 2-[(5-Bromo-2-Methylphenyl)Methyl]-5-(4-Fluorophenyl)Thiophene, 2-((5-bromo-2-methylphenyl)methyl)-5-(4-fluorophenyl)-thiophene, 2-((5-Bromo-2-methylphenyl)methyl-5-(4-fluorophenyl)thiophene, 2-(4-fluorophenyl)-5-[(5-bromo-2-methylphenyl)methyl]thiophene

Beschreibung

Applications 2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene is an antidiabetic agent that can be used to prepare Canagliflozin (C175190), a sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus.
References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 361.27
• Formel: C₁₈H₁₄BrFS
• Farbe/Form: Neat
• InChl: InChI=1S/C18H14BrFS/c1-12-2-5-15(19)10-14(12)11-17-8-9-18(21-17)13-3-6-16(20)7-4-13/h2-10H,11H2,1H3
• InChI Key: InChIKey=VLRIERSBZHUCOW-UHFFFAOYSA-N
• SMILES: Cc1ccc(Br)cc1Cc1ccc(-c2ccc(F)cc2)s1