Buclizine (piperazine-d8) Dihydrochloride

CAS: 129-74-8

Ref. TR-B689452

Produktinformation

• Name: Buclizine (piperazine-d8) Dihydrochloride
• Synonyme: 1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine-2,2,3,3,5,5,6,6-d8 dihydrochloride, 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride, 1-(4-Tert-Butylbenzyl)-4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazine Dihydrochloride, 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine hydrochloride, 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride, 1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride, Aphilan R, Bucladin S, Buclina, Buclizine HCl, Buclizine Hydrochloride, Buclodin, Histabutyzine hydrochloride, Longifene, NSC 25141, Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, dihydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2), Softran, Ucb 4445, Vibazine, Vibazine Hydrochloride

Beschreibung

Applications Buclizine (piperazine-d8) Dihydrochloride used as an antiemetic. It is the labelled version of B689450.
References Jorgensen, P.B., et al.: Curr. Ther. Res., 16, 1276 (1974); Adam, E.I.: J. Int. Med. Res., 15, 71 (1987)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 441.077
• Formel: C₂₈H₂₇D₈Cl₃N₂
• Farbe/Form: Neat
• InChl: InChI=1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H/i17D2,18D2,19D2,20D2
• InChI Key: InChIKey=MOYGZHXDRJNJEP-JYSKPPGCSA-N
• SMILES: [2H]C1([2H])N(Cc2ccc(C(C)(C)C)cc2)C([2H])([2H])C([2H])([2H])N(C(c2ccccc2)c2ccc(Cl)cc2)C1([2H])[2H]