(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid

CAS: 486460-00-8

Ref. TR-B692330

Produktinformation

• Name: (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
• Synonyme: Benzenebutanoic acid, beta-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (betaR)-, (betaR)-beta-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid, (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid, (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid, (3R)-3-[N-(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid, (R)-3-(((tert-Butoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butyric acid, (R)-3-[(tert-Butyloxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid, Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)-butyric acid, (3R)-N-(Tert-Butoxycarbonyl)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid, (3R)-3-(1,1-Dimethylethoxy Carbonyl) Amino]-4-(2,4,5-Trifluorophenyl) Butanoic Acid, Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid, (R)-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid, (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, (3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid, Benzenebutanoic acid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (3R)-, Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid, (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid, (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid, (R)-3-(tert-butoxy carbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid, 3(R)-tert-Butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid
• CAS: 486460-00-8

Beschreibung

Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.
References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 333.30
• Formel: C₁₅H₁₈F₃NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C15H18F3NO4/c1-15(2,3)23-14(22)19-9(6-13(20)21)4-8-5-11(17)12(18)7-10(8)16/h5,7,9H,4,6H2,1-3H3,(H,19,22)(H,20,21)/t9-/m1/s1
• InChI Key: InChIKey=TUAXCHGULMWHIO-SECBINFHSA-N
• SMILES: CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F