2-(p-sec-Butylphenyl)propionic Acid

CAS: 64451-76-9

Ref. TR-B692720

Produktinformation

• Name: 2-(p-sec-Butylphenyl)propionic Acid
• Synonyme: 2-[4-(1-Methylpropyl)-phenyl]propanoic Acid, Ibuprofen Imp. O (EP), Ibuprofen Impurity O

Beschreibung

Impurity Ibuprofen EP Impurity O
Applications 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 206.28
• Formel: C₁₃H₁₈O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C13H18O2/c1-4-9(2)11-5-7-12(8-6-11)10(3)13(14)15/h5-10H,4H2,1-3H3,(H,14,15)
• InChI Key: InChIKey=XOBVSMBVWPDJTC-UHFFFAOYSA-N
• SMILES: CCNC1(c2cccc(OC)c2)CCCCC1.Cl