6-Bromo-8-cyclopentyl-5-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one

CAS: 571188-81-3

Ref. TR-B694850

Produktinformation

• Name: 6-Bromo-8-cyclopentyl-5-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one
• Synonyme: 6-Bromo-8-cyclopentyl-2-methanesulfinyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one,, 6-Bromo-8-cyclopentyl-2-methylsulfinyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
• Marke: TRC

Beschreibung

Applications 6-Bromo-8-cyclopentyl-5-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one is used as a reactant in the preparation of pyrido[2,3-d]pyrimidin-7-one derivatives as selective inhibitors of cyclin-dependent kinases 4 and 6.
References VanderWel, S., et al.: J. Med. Chem., 48, 2371 (2005); Toogood, P., et al.: J. Med. Chem., 48, 2388 (2005);

Chemische Eigenschaften

• Molekulargewicht: 370.26
• Formel: C₁₄H₁₆BrN₃O₂S
• Farbe/Form: Neat
• InChl: InChI=1S/C14H16BrN3O2S/c1-8-10-7-16-14(21(2)20)17-12(10)18(13(19)11(8)15)9-5-3-4-6-9/h7,9H,3-6H2,1-2H3
• InChI Key: InChIKey=NNPLOKKYGFGHNO-UHFFFAOYSA-N
• SMILES: Cc1c(Br)c(=O)n(C2CCCC2)c2nc(S(C)=O)ncc12