Cabergoline

CAS: 81409-90-7

Ref. TR-C050000

Produktinformation

• Name: Cabergoline
• Synonyme: 1-Ethyl-3-[3-(dimethylamino)propyl]-3-[[(6aR,9R,10aR)-7-(prop-2-enyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]carbonyl]urea, (8-Beta)-(2-Propenyl), (8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide, (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide, (8β,10ξ)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide, 6-Allyl-N-[3-(Dimethylamino)Propyl]-N-(Ethylcarbamoyl)Ergoline-8-Carboxamide, Cabaser, Cabaseril, Dostine, Dostinex, Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-, Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-, (8β)-, FCE-21336,Cabaser,Dostinex, Galastop, N-(3-(Dimethylamino)Propyl)-N-((Ethylamino)Carbonyl)-6-Ergoline-8-Carboxamid, Sogilen, Velactis

Beschreibung

Stability Hygroscopic
Applications Cabergoline is an ergot derivative and a dopamine D2-receptor agonist (1,2,3). It inhibits the secretion of prolactin and growth hormone.
References (1) Kvernmo, T., et al.: Clin.Ther. 28 1065 (2006)(2) Boutinaud, M., et al.: J Dairy Sci. 99, 5707 (2016)(3) Hutton, J.T., et al.: Neurology, 46, 1062 (1996

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 451.60
• Formel: C₂₆H₃₇N₅O₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1
• InChI Key: InChIKey=KORNTPPJEAJQIU-XKCSPQBFSA-N
• SMILES: C=CCN1C[C@@H](C(=O)N(CCCN(C)C)C(=O)NCC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21