Canagliflozin 3-Glucuronide

Ref. TR-C175210

Produktinformation

• Name: Canagliflozin 3-Glucuronide
• Synonyme: (2S,3S,4S,5R,6R)-6-[(2S,5R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
• Marke: TRC
• Beschreibung: Applications Canagliflozin 3-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)

Chemische Eigenschaften

• Molekulargewicht: 620.64
• Formel: C₃₀H₃₃FO₁₁S
• Farbe/Form: Neat
• InChl: InChI=1S/C30H33FO11S/c1-13-2-3-15(10-16(13)11-18-8-9-20(43-18)14-4-6-17(31)7-5-14)26-25(37)27(21(33)19(12-32)40-26)41-30-24(36)22(34)23(35)28(42-30)29(38)39/h2-10,19,21-28,30,32-37H,11-12H2,1H3,(H,38,39)/t19?,21-,22+,23+,24-,25?,26+,27?,28+,30-/m1/s1
• InChI Key: InChIKey=TYOYRLJPOYQWCE-RRCUNSKQSA-N
• SMILES: Cc1ccc([C@@H]2OC(CO)[C@@H](O)C(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)C2O)cc1Cc1ccc(-c2ccc(F)cc2)s1