Candesartan Cilexetil-d11

CAS: 1261393-19-4

Ref. TR-C175582

Produktinformation

• Name: Candesartan Cilexetil-d11
• Synonyme: 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyl-d11-oxy)carbonyl]oxy]ethyl Ester, Atacand-d11, Blopress-d11, TCV 116-d11

Beschreibung

Applications Candesartan Cilexetil-d11 is the labeled analogue of Candesartan Cilexetil (C175580), is an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993), Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 621.73
• Formel: C₃₃H₂₃D₁₁N₆O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)/i4D2,5D2,6D2,10D2,11D2,24D
• InChI Key: InChIKey=GHOSNRCGJFBJIB-XLHVCENVSA-N
• SMILES: [2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(OC(=O)OC(C)OC(=O)c2cccc3nc(OCC)n(Cc4ccc(-c5ccccc5-c5nnn[nH]5)cc4)c23)C([2H])([2H])C1([2H])[2H]