Capecitabine

CAS: 154361-50-9

Ref. TR-C175650

Produktinformation

• Name: Capecitabine
• Synonyme: 5’-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl], 1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1H)-one, 5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, 5′-Deoxy-5-fluoro-N⁴-(pentyloxycarbonyl)cytidine, Capacetrine, Capecitabine Accord, Capecitabine Medac, Capecitabine SUN, Capecitabine Teva, Capecitibine, Capecytabine, Capiibine, Captabin, Carbamic acid, [1-(5-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester, Cytidine, 5′-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-, Ecansya, N4-[(pentyloxy)carbonyl]-5'-deoxy-5-fluorocytidine, N⁴-Pentyloxycarbonyl-5′-deoxy-5-fluorocytidine, Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate, R-340, Ro 09-1978/000, Ro-09-1978, Xeloda, Xeltabin, Carbamic acid, [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester

Beschreibung

Applications Capecitabine is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).
References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 359.35
• Formel: C₁₅H₂₂FN₃O₆
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
• InChI Key: InChIKey=GAGWJHPBXLXJQN-UORFTKCHSA-N
• SMILES: CCCCCOC(=O)Nc1nc(=O)n([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1F