1-Carboxy-3-adamantanol

CAS: 42711-75-1

Ref. TR-C177735

Produktinformation

• Name: 1-Carboxy-3-adamantanol
• Synonyme: 3-Hydroxy-tricyclo[3.3.1.13,7]decane-1-carboxylic Acid, 3-Hydroxy-1-adamantanecarboxylic Acid, 3-Carboxy-1-hydroxyadamantane, 3-Hydroxy-1-adamantanecarboxylic Acid, 3-Hydroxy--1-Amantane Carboxylic Acid, 3-Hydroxy-1-adamantanecarboxylic acid, 3-Hydroxy-1-Adamantane Carboxylic Acid, (5R,7R)-3-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate, 3-Hydroxytricyclo[3.3.1.1~3,7~]Decane-1-Carboxylic Acid
• CAS: 42711-75-1

Beschreibung

Applications 1-Carboxy-3-adamantanol is used in the synthesis of potent pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 which could be applied to a treatment of ulcers or in hormone therapy treatments relating to cortisol.
References Agarwal, A. et al.: Endocr. Res., 29, 411 (2004); Wang, H. et al.: Bioorg. Med. Chem. Lett., 21, 4146 (20110;

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 196.24
• Formel: C₁₁H₁₆O₃
• Farbe/Form: Off-White Solid
• InChl: InChI=1S/C11H16O3/c12-9(13)10-2-7-1-8(3-10)5-11(14,4-7)6-10/h7-8,14H,1-6H2,(H,12,13)
• InChI Key: InChIKey=CJJMAWPEZKYJAP-UHFFFAOYSA-N
• SMILES: O=C(O)C12CC3CC(CC(O)(C3)C1)C2