Castanospermine

CAS: 79831-76-8

Ref. TR-C185000

Produktinformation

• Name: Castanospermine
• Synonyme: (1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol, (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol, (1S,7R,8aR)-octahydroindolizine-1,6,7,8-tetrol, 1,6,7,8-Indolizinetetrol, octahydro-, (1S,6S,7R,8R,8aR)-, 1,6,7,8-Indolizinetetrol, octahydro-, [1S-(1α,6β,7α,8β,8aβ)]-, Castanospermine Castanospermum australe seeds, Castanospermine From Castanospermum*Australe Seed, NSC 614552, Octahydroindolizine-1,6,7,8-Tetrol
• CAS: 79831-76-8

Beschreibung

Applications Castanospermine is a plant alkaloid shown to be a potent inhibitor of lysosomal a-or beta- glucosidase. It also inhibits mammalian glucosidase 1 and beta-mannosidase from sweet almonds and fungal beta-xylosidase.
References Arch. Biochem. Biophys., 221, 593 (1983), Clin. Biochem., 17, 3 (1984), Trends Bio. Sci., 9, 32, (1984), J. Biol. Chem., 260, 15873-15879 (1985), FEBS, 1985, 28 (1986)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 189.21
• Formel: C₈H₁₅NO₄
• Farbe/Form: Off-White
• InChl: InChI=1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
• InChI Key: InChIKey=JDVVGAQPNNXQDW-TVNFTVLESA-N
• SMILES: O[C@H]1CN2CC[C@H](O)[C@@H]2[C@@H](O)[C@@H]1O