CDDO Imidazolide

CAS: 443104-02-7

Ref. TR-C228090

Produktinformation

• Name: CDDO Imidazolide
• Synonyme: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide, CDDO-Im, RTA 403, TP 235, CDDO-Imidazolide, 1-[2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl]-1H-imidazole

Beschreibung

Stability Light Sensitive
Applications CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular proliferation of human leukemia and breast cancer cell lines as well as being an effective therapeutic agent in the treatment of other types of cancers.
References Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008); Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2003); Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2005);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 541.72
• Formel: C₃₄H₄₃N₃O₃
• Farbe/Form: Neat
• SMILES: CC1(C)CC[C@]2(C(=O)n3ccnc3)CC[C@]3(C)[C@H](C(=O)C=C4[C@@]3(C)CC[C@H]3C(C)(C)C(=O)C(C#N)=C[C@]43C)[C@@H]2C1