Cefotaxime Proxetil

CAS: 217803-89-9

Ref. TR-C242935

Produktinformation

• Name: Cefotaxime Proxetil
• Synonyme: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)- (9CI), (1RS)-1-[[(1-Methylethoxy)carbonyl]oxy]ethyl (6R,7R)-3-(Acetoxymethyl)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, ACA-analogue of Cefpodoxime Proxetil, Cefpodoxime Proxetil Imp. E (EP)

Beschreibung

Impurity Cefpodoxime Proxetil EP Impurity E
Applications Cefotaxime Proxetil (Cefpodoxime Proxetil EP Impurity E) is an impurity of Cefotaxime (C242950), which is a broad spectrum third generation cephalosporin antibiotic. The name Cefotaxime applies to the isomer having a syn-methoxy imino group.
References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 585.61
• Formel: C₂₂H₂₇N₅O₁₀S₂
• Farbe/Form: Neat
• InChl: InChI=1S/C22H27N5O10S2/c1-9(2)35-22(32)37-11(4)36-20(31)16-12(6-34-10(3)28)7-38-19-15(18(30)27(16)19)25-17(29)14(26-33-5)13-8-39-21(23)24-13/h8-9,11,15,19H,6-7H2,1-5H3,(H2,23,24)(H,25,29)/b26-14-/t11?,15-,19-/m1/s1
• InChI Key: InChIKey=JRBKWVHQXXREQH-KMMUMHRISA-N
• SMILES: CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OC(C)OC(=O)OC(C)C)=C(COC(C)=O)CS[C@H]12)c1csc(N)n1