L-Cephalexin

CAS: 34632-04-7

Ref. TR-C256805

Produktinformation

• Name: L-Cephalexin
• Synonyme: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7ß(S*)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2S)-aminophenylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)- (9CI), (6R,7R)-7-[[(2S)-2-Amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(a-Amino-L-phenylacetamido)-3-deacetoxycephalosporanic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7b(S*)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2S)-aminophenylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)- (9CI), 7-(a-Amino-L-phenylacetamido)-3-deacetoxycephalosporanicacid

Beschreibung

Stability Hygroscopic
Applications The L-diastereomer of the β-lactam antibiotic Cephalexin (C256800). It is transported by PEPT1 (the oligopeptide transporter responsible for absorption of peptide nutrients in the small intestine) with high affinity, but is not metabolized by PEPT1 itself.
References Mitsuoka, K. et al.: Biol. Pharmac. Bull., 32, 1459 (2009); Snyder, N.J. et al.: Antimicrob. Agents Chemother., 41, 1649 (1997);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 347.39
• Formel: C₁₆H₁₇N₃O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11+,15+/m0/s1
• InChI Key: InChIKey=ZAIPMKNFIOOWCQ-FIXISWKDSA-N
• SMILES: CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@@H](N)c3ccccc3)[C@H]2SC1