C6 Ceramide-13C2,d2

CAS: 124753-97-5

Ref. TR-C262602

Produktinformation

• Name: C6 Ceramide-13C2,d2
• Synonyme: N-Hexanoy-D-sphingosine-13C2,d2, N-Caproyl-D-sphingosine-13C2,d2, Caproyl Ceramide-13C2,d2, Caproyl Ceramide, Ceramide C6, C6 Ceramide Of D-Erythro-C8-Sphingosine, C6-D-Erythro-Ceramide, C8 Sphingoid Base, D-Erythro-Sphingosine, N-Hexanoyl-, 06:0 Ceramide, N-(1,3-dihydroxyoctadec-4-en-2-yl)hexanamide

Beschreibung

Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
References Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 401.63
• Formel: C₂₂₁₃C₂H₄₅D₂NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23+/m0/s1/i21+1D2,22+1
• InChI Key: InChIKey=NPRJSFWNFTXXQC-NICJHGTRSA-N
• SMILES: [2H][13C]([2H])(O)[13C@H](NC(=O)CCCCC)[C@H](O)/C=C/CCCCCCCCCCCCC