(R)-Cetirizine-d4 Dihydrochloride

CAS: 1133210-23-7

Ref. TR-C281108

Produktinformation

• Name: (R)-Cetirizine-d4 Dihydrochloride
• Synonyme: 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride, (-)-Cetirizine-d4 Dihydrochloride, Levocetirizine-d4 Dihydrochloride
• Marke: TRC
• Beschreibung: Applications Labelled (R)-Cetirizine (C281100). A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

Chemische Eigenschaften

• Molekulargewicht: 465.83
• Formel: C₂₁H₂₃D₄Cl₃N₂O₃
• Farbe/Form: Off White
• InChl: InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)
• InChI Key: InChIKey=ZKLPARSLTMPFCP-KNFDVUFYSA-N
• SMILES: [2H]C([2H])(OCC(=O)O)C([2H])([2H])N1CCN([C@H](c2ccccc2)c2ccc(Cl)cc2)CC1