CHIR 99021 Hydrochloride Salt

CAS: 252917-06-9

Ref. TR-C292157

Produktinformation

• Name: CHIR 99021 Hydrochloride Salt
• Synonyme: 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-, 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-, 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile, Chir 911, Chir 99201, Chir-99021, Chir99021, Cihr 99021, Ct 99021, GSK 3 inhibitor XVI, Gsk 3Ixv, Laduviglusib

Beschreibung

Applications CHIR 99021 Hydrochloride is an inhibitor of glycogen synthase kinase 3, which mimics Wnt signaling in preadipocytes. CHIR 99021 stabilizes free cytosolic β-​catenin and inhibits adipogenesis by blocking induction of CCAAT​/enhancer-​binding protein α and peroxisome proliferator-​activated receptor γ.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bennett, C., et al.: J. Bio. Chem., 277, 30998 (2002);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 465.343646
• Formel: C₂₂H₁₈Cl₂N₈•xHCl
• Farbe/Form: Neat