CHIR 99021 Hydrochloride Salt

CAS: 252917-06-9

Ref. TR-C292157

Produktinformation

• Name: CHIR 99021 Hydrochloride Salt
• Synonyme: 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile
• Marke: TRC
• Beschreibung: Applications CHIR 99021 Hydrochloride is an inhibitor of glycogen synthase kinase 3, which mimics Wnt signaling in preadipocytes. CHIR 99021 stabilizes free cytosolic β-​catenin and inhibits adipogenesis by blocking induction of CCAAT​/enhancer-​binding protein α and peroxisome proliferator-​activated receptor γ. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Bennett, C., et al.: J. Bio. Chem., 277, 30998 (2002)

Chemische Eigenschaften

• Molekulargewicht: 465.343646
• Formel: C₂₂H₁₈Cl₂N₈•xHCl
• Farbe/Form: Neat
• InChl: InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)