N-​[4-​Chloro-​2-​(2-​chlorobenzoyl)​phenyl]​-​2-​[(2-​hydroxyethyl)​amino]​acetamide

CAS: 24234-92-2

Ref. TR-C293005

Produktinformation

• Name: N-​[4-​Chloro-​2-​(2-​chlorobenzoyl)​phenyl]​-​2-​[(2-​hydroxyethyl)​amino]​acetamide
• Synonyme: 4'-Chloro-2'-(o-chlorobenzoyl)-2-[(2-hydroxyethyl)amino]acetamide

Beschreibung

Applications N-​[4-​Chloro-​2-​(2-​chlorobenzoyl)​phenyl]​-​2-​[(2-​hydroxyethyl)​amino]​acetamide is an impurity of Cloxazolam (C587475). Cyclization of N-​[4-​Chloro-​2-​(2-​chlorobenzoyl)​phenyl]​-​2-​[(2-​hydroxyethyl)​amino]​acetamide can produce Cloxazolam. Cloxazolam is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. Cloxazolam is metabolized into the active metabolite Delorezepam (D230675).
References Ji, M., et al. Zhongguo Yaoke Daxue Xuebao, 25, 69 (1994); Oliveira-Silva, D. et al.: Biomed. Chrom., 23, 1266 (2009); Kamioka, T. et al.: Psychopharmacol., 52, 17 (1977); Fischer-Cornelssen, K.A. et al.: Arzneim.-Forsch., 31, 1757 (1981);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 367.23
• Formel: C₁₇H₁₆Cl₂N₂O₃
• Farbe/Form: Light Yellow
• InChl: InChI=1S/C17H16Cl2N2O3/c18-11-5-6-15(21-16(23)10-20-7-8-22)13(9-11)17(24)12-3-1-2-4-14(12)19/h1-6,9,20,22H,7-8,10H2,(H,21,23)
• InChI Key: InChIKey=PIJVIEBVNDIKTA-UHFFFAOYSA-N
• SMILES: O=C(CNCCO)Nc1ccc(Cl)cc1C(=O)c1ccccc1Cl