1-Chloro-N,N-2-trimethylpropenylamine (>90%)

CAS: 26189-59-3

Ref. TR-C349260

Produktinformation

• Name: 1-Chloro-N,N-2-trimethylpropenylamine (>90%)
• Synonyme: 1-Chloro-N,N,2-trimethyl-1-propen-1-amine, (1-Chloro-2-methylprop-1-en-1-yl)dimethylamine, (1-Chloro-2-methylpropenyl)dimethylamine, 1-Chloro-1-(dimethylamino)-2-methylpropene, 1-Chloro-N,N,2-trimethyl-1-propenylamine, 1-Chloro-N,N,2-trimethylprop-1-en-1-amine, 1-Chloro-N,N-2-trimethylpropenylamine, 1-Chloro-N,N-dimethyl-2-methyl-1-propenylamine, 1-Chloro-N,N-dimethyl-2-methylprop-1-en-1-amine, Ghosez's reagent, N-(1-Chloro-2-methylprop-1-enyl)-N,N-dimethylamine
• Marke: TRC

Beschreibung

Stability Unstable in solution. Small amounts of precipitate should have no effect on use.
Applications 1-Chloro-N,N-2-trimethylpropenylamine acts as a reagent in the synthesis and antitumor activity of (-)-bassianolide in human cancer cells through cell cycle arrest. Enantioselective total synthesis of nannocystins A and A0 as elongation factor 1 inhibitors. Total synthesis of (-)-caprazamycin A with antibacterial activity against Mycobacterium tuberculosis (TB) via diastereoselective aldol reaction.
References Mun, B., et al.: Bioorg. Chem., 69, 64 (2016); Huang, J., et al.: Org. Lett., 18, 4702 (2016); Nakamura, H., et al.: Angew. Chem., Int. Ed., 54, 3136 (2015)

Chemische Eigenschaften

• Molekulargewicht: 133.62
• Formel: C₆H₁₂ClN
• Reinheit: >90%
• Farbe/Form: Neat
• InChl: InChI=1S/C6H12ClN/c1-5(2)6(7)8(3)4/h1-4H3
• InChI Key: InChIKey=GQIRIWDEZSKOCN-UHFFFAOYSA-N
• SMILES: CC(C)=C(Cl)N(C)C