4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester

CAS: 1374033-38-1

Ref. TR-C363825

Produktinformation

• Name: 4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester
• Synonyme: 4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine methyl ester (ACI)

Beschreibung

Applications 4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester is an intermediate in the synthesis of metabolites of Melphalan (M216900), a chemotherapy drug that chemically alters DNA through alkylation of the DNA nucleotide guanine which results in linkages to occur between strands.
References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 356.84
• Formel: C₁₇H₂₅ClN₂O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C17H25ClN2O4/c1-17(2,3)24-16(22)20-14(15(21)23-4)11-12-5-7-13(8-6-12)19-10-9-18/h5-8,14,19H,9-11H2,1-4H3,(H,20,22)