3-(4-Chlorobenzal)phthalide

CAS: 20526-97-0

Ref. TR-C364515

Produktinformation

• Name: 3-(4-Chlorobenzal)phthalide
• Synonyme: Azelastine Imp. E (EP), Azelastine USP Related Compound E, Azelastine USP RC E,1(3H)-Isobenzofuranone, 3-[(4-chlorophenyl)methylene]-, Phthalide, 3-(p-chlorobenzylidene)- (6CI,7CI,8CI), 3-(4-Chlorobenzylidene)-2-benzofuran-1(3H)-one, 3-(p-Chlorobenzylidene)phthalide, Azelastine Related Compound E (USP), Azelastine Hydrochloride Imp. E (EP), Azelastine Related Compound E, Azelastine Hydrochloride Impurity E, Azelastine Impurity E, 1(3H)-Isobenzofuranone, 3-[(4-chlorophenyl)methylene]-, 3-(4-chlorobenzylidene)-2-benzofuran-1(3H)-one, 3-(4-chlorobenzylidene)isobenzofuran-1(3H)-one, 3-[(4-Chlorophenyl)methylene]-1(3H)-isobenzofuranone, 3-[(4-Chlorophenyl)methylidene]-2-benzofuran-1-one, Phthalide, 3-(p-chlorobenzylidene)-

Beschreibung

Impurity Azelastine EP Impurity E /Azelastine USP RC E
Applications Stilbene-related benzalphthalide derivative with with potential anti-HIV and leishmanicidal activity. It has anxiolytic effects and maybe useful in the development of a non-benzodiazepinic and non-nitrogenated antianxiety agents.An impurity arising in the synthesis of azelastine (A808250).
References Zamilpa, A. et al.: Bioorg. Med. Chem. Lett., 15, 3483 (2005); Bedoya, L.M. et al.: Bioorg. Med. Chem. Lett., 16, 4075 (2006); del Olmo, E. et al.: Bioorg. Med. Chem. Lett., 11, 2123 (2001);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 256.68
• Formel: C₁₅H₉ClO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C15H9ClO2/c16-11-7-5-10(6-8-11)9-14-12-3-1-2-4-13(12)15(17)18-14/h1-9H
• InChI Key: InChIKey=OHRFHJYUEWVXBD-NTEUORMPSA-N
• SMILES: O=C1OC(=Cc2ccc(Cl)cc2)c2ccccc21