2-Chloro-4-fluorobenzoic Acid

CAS: 2252-51-9

Ref. TR-C364835

Produktinformation

• Name: 2-Chloro-4-fluorobenzoic Acid
• Synonyme: 1-Chloro-2-Fluorobezene, 2-Chloro-4-Fluorobenzoate, 2-Chloro-4-Fluorobenzoic, 2-Chloro-4-fluorobenzoic acid 99%, 2-Chloro-4-fluorobenzoicacid99%, 2-[4-(Trifluoromethyl)Phenyl]Propan-2-Ol, Benzoic acid, 2-chloro-4-fluoro-, Rarechem Al Bo 0405, Timtec-Bb Sbb003795
• CAS: 2252-51-9

Beschreibung

Applications 2-Chloro-4-fluorobenzoic Acid s a useful synthetic intermediate. It can be used to prepare aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists. It can also be used to synthesize (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists.
References Barnett, H., et al.: Bioorg. Med. Chem. Lett., 19, 158 (2009); Tsukamoto, I., et al.: Bioog. Med. Chem., 16, 9524 (2008)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 174.56
• Formel: C₇H₄ClFO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C7H4ClFO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)
• InChI Key: InChIKey=GRPWQLDSGNZEQE-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(F)cc1Cl