8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

CAS: 117811-17-3

Ref. TR-C365218

Produktinformation

• Name: 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

Beschreibung

Applications 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is an intermediate in synthesizing Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate (E902775). It is an impurity of loratadine (L469575), which is a nonsedating-type histamine H1-receptor.
References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 340.85
• Formel: C₂₀H₂₁ClN₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C20H21ClN2O/c1-23-11-8-16(9-12-23)20(24)18-7-6-17(21)13-15(18)5-4-14-3-2-10-22-19(14)20/h2-7,10,13,16,24H,8-9,11-12H2,1H3
• InChI Key: InChIKey=WTWJHFHSSVVYJK-UHFFFAOYSA-N
• SMILES: CN1CCC(C2(O)c3ccc(Cl)cc3C=Cc3cccnc32)CC1