2-Chloro-2',6'-dimethyl-d6-acetanilide

CAS: 1131-01-7

Ref. TR-C365377

Produktinformation

• Name: 2-Chloro-2',6'-dimethyl-d6-acetanilide
• Synonyme: 2-Chloro-N-(2,6-dimethyl-d6-phenyl)acetamide, 1-Chloroacetylamino-2,6-dimethyl-d6-benzene, 2-Chloro-2',6'-acetoxylidide-d6, 2',6'-Dimethyl-d6-2-chloroacetanilide, Chloroacetamido-2,6-xylidine-d6, Chloroaceto-2,6-xylidide-d6, N-(2,6-Dimethyl-d6-phenyl)-2-chloroacetamide, N-(2,6-Xylyl)chloroacetamide-d6, N-Chloroacetyl-2,6-dimethyl-d6-aniline, NSC 37260-d6, 1-Chloroacetylamino-2,6-dimethylbenzene, 2-Chloro-2',6'-acetoxylidide, 2-Chloro-2,6-acetoxylidide, 2-Chloro-2,6-dimethylacetanilide, 2-Chloroaceto-2,6-xylidide, 2′,6′-Acetoxylidide, 2-chloro-, 2′,6′-Dimethyl-2-chloroacetanilide, Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-, Chloroacetamido-2,6-xylidine, Chloroaceto-2,6-xylidide, N-(2,6-Dimethylphenyl)-2-chloroacetamide, N-(2,6-Dimethylphenyl)-2-chloroethanamide, N-(2,6-Dimethylphenyl)chloroacetamide, N-(2,6-Xylyl)chloroacetamide, N-(Chloroacetyl)-2,6-diethylaniline, N-Chloroacetyl-2,6-dimethylaniline, NSC 37260, alpha-Chloro-2,6-dimethylacetanilide, 2-Chloro-N-(2,6-dimethylphenyl)acetamide

Beschreibung

Stability Light Sensitive
Applications 2-Chloro-2',6'-dimethyl-d6-acetanilide is the labeled analogue of 2-Chloro-2',6'-dimethylacetanilide (C365375), an intermediate of Lidocaine (L397800), a local anesthetic; antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
References Moen, A., et al.: Biocatal. Biotransform., 23, 45 (2005); Yogeeswari, P., et al.: Bioorg. Med. Chem. Lett., 17, 3712 (2007); Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971); Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973); Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985); Davies, P.S., et al.: Drugs, 64, 937 (2004)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 203.7
• Formel: C₁₀H₆D₆ClNO
• Farbe/Form: Neat
• InChl: InChI=1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)/i1D3,2D3
• InChI Key: InChIKey=FPQQSNUTBWFFLB-WFGJKAKNSA-N
• SMILES: [2H]C([2H])([2H])c1cccc(C([2H])([2H])[2H])c1NC(=O)CCl