3'-Chloro-3'-Deoxythymidine

CAS: 25526-94-7

Ref. TR-C365575

Produktinformation

• Name: 3'-Chloro-3'-Deoxythymidine
• Synonyme: Zidovudine Imp. B (EP), 892U81, GW 297366X, USP Zidovudine Related Compound B, Ph Eur Zidovudine Impurity B, 3-chloro-3-deoxythymidine 892U81, Zidovudine Related Compound B, Zidovudine Impurity B,1-(3-Chloro-2,3-dideoxy-ß-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(3-Chloro-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

Beschreibung

Impurity Zidovudine EP Impurity B
Applications 3'-Chloro-3'-deoxythymidine (Zidovudine EP Impurity B) is an impurity of 3'-Azido-3'-deoxythymidine (A825000), a potent and selective inhibitor of HIV-1 replication and a potential antiviral agent.
References Navaneethan, G., et al.: J. Food. Drug Anal., 20, 446 (2012); Srivastav, N.C., et al.: Bioorg. Med. Chem., 18, 7542 (2010); Shakya, N., et al.: J. Med. Chem., 53, 4130 (2010); Fukushima, M., et al.: BIochem. Pharmacol., 59, 1227 (2000);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 260.67
• Formel: C₁₀H₁₃ClN₂O₄
• Farbe/Form: Beige
• InChl: InChI=1S/C10H13ClN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
• InChI Key: InChIKey=KQVJDKGDGLWBQT-JECWYVHBSA-N
• SMILES: Cc1cn(C2C[C@@H](Cl)C(CO)O2)c(=O)[nH]c1=O