2-Chloroethyl Methanethiosulfonate

CAS: 13700-02-2

Ref. TR-C366125

Produktinformation

• Name: 2-Chloroethyl Methanethiosulfonate
• Synonyme: Methanesulfonothioic Acid S-(2-Chloroethyl) Ester, 2-Chloro-ethanethiol Methanesulfonate

Beschreibung

Stability Moisture Sensitive
Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Egan, T.M., et al.: The Journal of Neuroscience, 18(7), 2350 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 174.67
• Formel: C₃H₇ClO₂S₂
• Farbe/Form: Clear Colourless Oil
• InChl: InChI=1S/C3H7ClO2S2/c1-8(5,6)7-3-2-4/h2-3H2,1H3
• InChI Key: InChIKey=LMGGUMRZPMEEEK-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)SCCCl