7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

CAS: 160129-45-3

Ref. TR-C366265

Produktinformation

• Name: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
• Synonyme: 7-Chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
• Marke: TRC

Beschreibung

Applications 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one is an intermediate in the synthesis of Tolvaptan (T536650) (OPC-41061), an orally active nonpeptide arginine vasopressin V2 receptor antagonist
References Kondo, K., et al.: Bioorg. Med. Chem., 7, 1743 (1999);

Chemische Eigenschaften

• Molekulargewicht: 195.65
• Formel: C₁₀H₁₀ClNO
• Farbe/Form: Neat
• InChl: InChI=1S/C10H10ClNO/c11-7-3-4-9-8(6-7)10(13)2-1-5-12-9/h3-4,6,12H,1-2,5H2
• InChI Key: InChIKey=AHESNFIUAHTYGS-UHFFFAOYSA-N
• SMILES: O=C1CCCNc2ccc(Cl)cc21